Cyclosporine A

Sort List By: Replies Recent Votes Views

Cyclosporine A (also Ciclosporin) is an immunomodulator, a drug that can weaken or modulate the activity of the immune system. It is most often used in post-organ transplant treatment to reduce the risk of organ rejection by suppressing the patient’s immune system, but it has also been used in psoriasis and rheumatoid arthritis. It can be taken orally or by injection, and is useful for patients with Crohn’s disease when taken intravenously and in high doses. Cyclosporine A acts more rapidly in the body than 6-Mercaptopurine or azathioprine, taking one to two weeks for onset of action instead of several months.

Cyclosporine A works by reducing the function of T-cells in the immune system. Side effects include, but are not limited to, increased risk of infection, decreased kidney function, headache, nausea, diarrhea, and high blood pressure.